ea0014p23 | (1) | ECE2007
Diness Signe
, Rasmussen Æse Krogh
, Bendtzen Klaus
, Kosteljanetz Michael
, Feldt-Rasmussen Ulla
Aim: to establish a human in vitro system for the study of pituitary cells in culture and subsequently to study the influence of the pro-inflammatory cytokines interleukin (IL)-1β and tumour necrosis factor (TNF)-α on the function of the somatotrophic cells inclusive the ability of the cells to produce IL-6 and IL-8.Methods: Pituitary adenomas were obtained from hypophysectomies of patients with acromegaly. The tissue was enzymatically d...